THE INFLUENCE OF RENAL FUNCTION AND LIVER ON THE EFFECTIVENESS OF THERAPY WITH WARFARIN BY PATIENTS WITH MECHANICAL PROSTHETIC HEART VALVES

Iskenderov Bakhram Guseynovich, Doctor of medicine, professor, sub-department of therapeutics, cardiology and functional diagnostics, Penza state institute of advanced medical studies, iskenderovbg@mail.ru
Vasilyev Denis Alexandrovich, Attending physician, sub-department of clinical laboratory diagnostics, Penza state institute of advanced medical studies, Silent.pnz@mail.ru

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Results of postoperative research of influence kidneys and liver diseases to the effectiveness of warfarin in patients with mechanical heart valves were stated. The analysis of the results determined the dependence between a functional condition of a liver and kidneys and the doses of warfarin necessary for maintenance of target level of anticoagulation.

anticoagulation therapy, heart valve diseases, mechanical heart valves.